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<blockquote data-quote="oldngray" data-source="post: 1673681" data-attributes="member: 45230"><p>Nope. You are wrong again. Generics have identical active ingredients but are usually a slightly different formulation. It is the "inactive" ingredients that can make a difference.</p><p></p><p><strong>FDA</strong> requires that generic forms of prescription medication contain the same active ingredient as the brand name. However, the agency allows the generic drug to include different inactive components, such as binders to keep the pill together and release agents to dispense the ingredients.</p><p></p><p>However, some generic drugs' dissolution processes has been found to significantly alter the effectiveness of the drug compared to the name-brand medication.</p><p></p><p>According to ABC News, determining the drug's dissolution process is important, because Wellbutrin XL is an "extended release" drug, meaning it intermittently releases the drug's active ingredient into a patient's system. Generic drugs are not required to have the same release mechanism as the brand-name medications. </p><p></p><p></p><p>The ConsumerLab.com researchers found that after two hours, 34% of Budeprion's active ingredient had been released, compared with just 8% for Wellbutrin. ConsumerLab.com president Ted Cooperman calls the results "shocking," adding, "You're getting a burst of medication coming out very early on with the generic that you shouldn't be getting." According to ABC News, the initial large burst of Budeprion's active ingredient would cause the patient's energy to spike, leaving few active ingredients in the patient's body for the remainder of the day and potentially causing unexpected side effects.</p><p><a href="http://www.advisory.com/daily-briefing/2014/09/29/generic-pills-arent-always-identical-to-brand-name-ones" target="_blank">http://www.advisory.com/daily-briefing/2014/09/29/generic-pills-arent-always-identical-to-brand-name-ones</a></p><p></p><p>If you want to google it yourself you will see similar articles. Or have more personal experience taking both generic and name brand medications. As I said before, sometimes there will be no noticeable difference but other times there is a difference.</p></blockquote><p></p>
[QUOTE="oldngray, post: 1673681, member: 45230"] Nope. You are wrong again. Generics have identical active ingredients but are usually a slightly different formulation. It is the "inactive" ingredients that can make a difference. [B]FDA[/B] requires that generic forms of prescription medication contain the same active ingredient as the brand name. However, the agency allows the generic drug to include different inactive components, such as binders to keep the pill together and release agents to dispense the ingredients. However, some generic drugs' dissolution processes has been found to significantly alter the effectiveness of the drug compared to the name-brand medication. According to ABC News, determining the drug's dissolution process is important, because Wellbutrin XL is an "extended release" drug, meaning it intermittently releases the drug's active ingredient into a patient's system. Generic drugs are not required to have the same release mechanism as the brand-name medications. The ConsumerLab.com researchers found that after two hours, 34% of Budeprion's active ingredient had been released, compared with just 8% for Wellbutrin. ConsumerLab.com president Ted Cooperman calls the results "shocking," adding, "You're getting a burst of medication coming out very early on with the generic that you shouldn't be getting." According to ABC News, the initial large burst of Budeprion's active ingredient would cause the patient's energy to spike, leaving few active ingredients in the patient's body for the remainder of the day and potentially causing unexpected side effects. [URL]http://www.advisory.com/daily-briefing/2014/09/29/generic-pills-arent-always-identical-to-brand-name-ones[/URL] If you want to google it yourself you will see similar articles. Or have more personal experience taking both generic and name brand medications. As I said before, sometimes there will be no noticeable difference but other times there is a difference. [/QUOTE]
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