UPS Healthcare Expands Global Cold Chain Logistics Network


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Marken, UPS Healthcare's clinical trial logistics unit, adds significant capacity to support increased demand for cell and gene therapies

Marken, the clinical trial logistics operation with UPS Healthcare, has expanded its global network to support increased demand for its clinical drug supply chain services, particularly for cell and gene clinical trials. Plans for the remainder of 2021 and 2022 will support accelerated demand for mRNA therapies, cell and gene therapies, early access and managed access programs. Expansion plans include new locations, expanded cold chain services and packaging solutions.


"We are accelerating the expansion of our clinical supply chain network across all regions to provide increased flexibility and global access for our partners, including access in emerging markets like South Korea and Sub-Saharan Africa," said Ariette van Strien, president of Marken. "These investments are especially critical for cell and gene therapy developers, where we see increased innovation enabled by mRNA, CAR-T, and viral vectors. With the FDA expecting to approve 10 to 20 cell and gene therapy products per year by 2025, our industry-leading network is designed to simplify the transition from clinical trials to commercialization."
Marken's ongoing and planned investments include:
  • The addition of over 100,000 square feet of GMP-compliant depot operations in Louisville, KY, Great Valley, PA, and Seoul, South Korea.
  • A new GMP depot facility in Kiev, Ukraine
  • A new GDP depot facility in Osaka, Japan
  • New locations in Nairobi, Kenya and Accra, Ghana
  • Expansion of its kit assembly facility in Shanghai, China
  • New liquid nitrogen (LN2) filling stations within each of its global cell and gene centers of excellence
  • Infrastructure expansion at its facilities in Belgium, France, South Africa, India, Taiwan, China, and Singapore
  • Packaging and technology enhancements for real-time location tracking and temperature monitoring of cell and gene therapy shipments
In addition to GMP storage, Marken will be able to track highly sensitive cell and gene therapy, compassionate use, and early access program shipments from its Ukraine facility. This new control center, combined with the existing control center in Durham, NC, US, will enhance 24/7/365 global monitoring of all complex shipments, including cell and gene shipments.

Marken's clinical supply chain network reinforces UPS Healthcare's continued investment in accelerating cold chain capabilities across the world. In 2021, UPS Healthcare has invested in roughly 390,000 square feet of cold chain GMP storage coolers and freezers installed at UPS facilities to support the storage of biologics ranging from 2°C to as low as -80°C. Wes Wheeler, president of UPS Healthcare, commented, "UPS Healthcare maintains high standards for excellence in cold chain delivery and logistics, and these current and future investments in innovative solutions will ensure we keep pushing the bar higher."
For further details of Marken's global network and to view an interactive map, please visit

About UPS Healthcare and Marken
UPS Healthcare has 11 million square feet of GMP- and GDP-compliant healthcare distribution space in 128 facilities in 32 countries. UPS Healthcare services include: inventory management, temperature-controlled packaging and shipping, storage and fulfillment of medical devices, labs and clinical trial logistics. UPS Healthcare's global infrastructure, its newest UPS Premier visibility service, its track and trace technology, and its global quality system are well-suited to meet today's complex logistics demands for the pharmaceutical, medical device and laboratory diagnostic industries.

Marken offers a state-of-the-art GMP-compliant depot network and logistic hubs for clinical drug product storage and distribution in 58 locations worldwide, while maintaining the leading position for Direct-to-Patient and Home Healthcare services, biological sample shipments and biological kit production. Marken's dedicated 1,691 staff members manage 110,000 drug product and biological sample shipments every month at all temperature ranges in more than 220 countries. Additional services such as ancillary material sourcing, storage and distribution, shipment lane verification and qualifications, as well as GDP, regulatory and compliance consultancy add to Marken's unique position in the pharma and logistics industry.

Providing flexible supply chain solutions for today's adaptive trial landscape, we ship materials at all temperature ranges to investigator sites, depots, and directly to patients' homes.