Use a map and learn the number breaks - you'll never get your day done if you type in every stop, especially in order that EDD gives you, into a GPS.
For example, in my city - the Avenues 99% of the time run east and west, and the streets north and south. So2207 E 25th Avenue would be near the corner of 22nd street and 25th avenue. Learn where the epicenter of your city is - where all east/west and north/south derives from.
In a rual city that I deliver airs to, the 4 digit addresses mean that its a house that faces (99% of the time) a NORTH/SOUTH street and the 5 digit addresses face an east/west street. The higher number the 4 digits are, the farther NORTH the place is - and the higher number 5 digit addresses are farther EAST.
However - when I get in a jam or in suburbia hell - I break out my Garmin iQue M4. I bought it back in early 2006 and its been well worth the $400 I paid for it. Its a PDA with GPS on it, and is battery powered. I could get about 3-4 hours of constant use out of it when it was new, but now that its been used for personal and work - the battery only lasts about an hour. Sometimes I get lucky and get a truck with a cigarette lighter and then I'm good to go. Its much safer than holding a map with your hand and trying to navigate some of the subdivisions around here. The M4 has been discontinued so look around and see what other GPS/PDA's Garmin offers.