It seems like it varies from Center to Center and District to District.
So the best answer seems to be - Do what you're told. UPS is setup to allow for a greater control at the Center and District level, no matter how screwed up the decision may be.
Logically, even if we know the location is closed, the package should be still attempted. That's what we are paid for after all and advertise 3 attempts. It sounds like some are trying to lower the cost to serve by no loading certain packages.
Last week ran into two situations where this caused problems. First was an NDA AM where the driver drove by the location because there were no lights on and they are normally closed. Guess what, the owner was there waiting for a shipment that cost him a lot of business. Location was never attempted and marked as closed.
Second was with a business that normally isn't open until late in the afternoon. Driver had a large NDA package. Marked it DR in part to make commit (The package was for some reason marked resi) and left it . . . in his truck. Upon being asked stated that he left it inside the front door as he had keys to the location, but the customer couldn't find it. There were two people inside the front steps waiting for the package. Several messages later admitted it was still in his truck and broke trace to get it to the customer.
This is why even though you know it is scheduled to be closed, we should still be attempting a delivery. We get paid to attempt 3 times, let it sit on a postcard, and only then return the package. If we have to return the package, we charge for that too. That's easy money for doing what we promised the customer in the first place.
Just my two cents